Hydrogen Bromide → HCID 14441919, compound

Participants

Reaction Steps

14.4 g 3-(4-Chloro-2-fluoro-5-methoxyphenylimino)-1-methylhexahydro-3H-oxazolo[3,4-a]pyridine was heated under reflux with 25 ml 48% hydrobromic acid for 5 hours. After cooling it was neutralised with 40% caustic soda and extracted with ethyl acetate. The organic phase was dried over magnesium sulphate, concentrated and the residue recrystallised from petroleum ether.

Provenance & Evidence