HCID 54294522, compound → HCID 19887623, compound

HRID 654467Notes

Reaction equation

HRID 654467 reaction equation
[CH3:1][N:2]([CH2:9][CH2:10][O:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][OH:17])=[CH:14][CH:13]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>[O-2].[Mn+4].[O-2].ClCCl>[CH3:1][N:2]([CH2:9][CH2:10][O:11][C:12]1[CH:13]=[CH:14][C:15]([CH:16]=[O:17])=[CH:18][CH:19]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 1

HCID 54294522HCID 54294522, compound

Product 1

HCID 19887623HCID 19887623, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

A mixture of 4-[2-(N-methyl-N-phenylamino)ethoxy]benzyl alcohol (3.36 g), manganese (IV) oxide (11.3 g) and dichloromethane (150 ml) were stirred at room temperature overnight. The mixture was filtered through a Soxhlet thimble and the residue extracted with refluxing dichloromethane for 2.5 hours. The solvent was evaporated to afford the title compound, an oil, which was used without further purification.

Workup

  1. filtrationThe mixture was filtered through a Soxhlet thimble
  2. extractionthe residue extracted with refluxing dichloromethane for 2.5 hours
  3. customThe solvent was evaporated

Sources & evidence

ORD record
ord-dae811d40dbc4399bac5525f59ccd5c1
Source dataset
uspto-grants-1992_07
Patent number
US05132317

Reaction notes

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