反应详情

To a solution of 2.0 g of tetrafluoroisophthalonitrile in 20 ml of acetonitrile, 0.6 ml of 28% aqueous ammonia was dropwise added. After the dropwise addition, the mixture was stirred at room temperature for one hour. An aqueous sodium bicarbonate solution was added to the mixture and the resultant mixture was extracted with chloroform and was washed with an aqueous sodium chloride solution. After drying with sodium sulfate, the chloroform was distilled off to obtain yellow crystal. The resultant crystal was recrystallized from chloroform to obtain 1.2 g (61% yield) of the desired compound No. 1.

1. additionAfter the dropwise addition
2. extractionthe resultant mixture was extracted with chloroform
3. washwas washed with an aqueous sodium chloride solution
4. dry with materialAfter drying with sodium sulfate
5. distillationthe chloroform was distilled off
6. customto obtain yellow crystal
7. customThe resultant crystal was recrystallized from chloroform