Sodium Hydroxide → Sodium 2-chloro-3-benzyloxypropionate

HRID 654564Notes

Reaction equation

HRID 654564 reaction equation
[Cl:1][CH:2]([CH2:6][O:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([OH:5])=[O:4].[OH-].[Na+:16]>O>[Cl:1][CH:2]([CH2:6][O:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([O-:5])=[O:4].[Na+:16]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 198877953-(Benzyloxy)-2-chloropropanoic acid

Product 1

HCID 23721614Sodium 2-chloro-3-benzyloxypropionate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

85 g of 2-chloro-3-benzyloxypropionic acid (0.396 mol) were suspended in 550 ml of water and neutralized to pH 7 with 10% sodium hydroxide. After stirring for 15 min, the resulting aqueous solution was washed with ethyl ether and evaporated to dryness under vacuum to give the desired compound.

Workup

  1. washthe resulting aqueous solution was washed with ethyl ether
  2. customevaporated to dryness under vacuum

Sources & evidence

ORD record
ord-ce6d7bc3a6f446ad8c73792b287efab1
Source dataset
uspto-grants-1992_07
Patent number
US05132409

Reaction notes

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