Aniline → 2-Anilinonicotinic acid

HRID 654761노트

반응식

HRID 654761 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:9]1[N:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]([OH:13])=[O:12]>C1(C)C(C)=CC=CC=1>[C:2]1([NH:1][C:9]2[N:17]=[CH:16][CH:15]=[CH:14][C:10]=2[C:11]([OH:13])=[O:12])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 6115AnilineHCID 762582-Chloronicotinic acid

생성물 1

HCID 14817992-Anilinonicotinic acid

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

50 ml of distilled aniline and 43.2 g of 2-chloronicotinic acid are mixed in 126 ml of xylene. The mixture is brought to reflux for 4 hours. It is allowed to cool and the precipitate is filtered off and washed several times with water.

후처리

  1. temperatureto reflux for 4 hours
  2. temperatureto cool
  3. filtrationthe precipitate is filtered off
  4. washwashed several times with water

출처 및 근거

ORD 기록
ord-247b5eb095e94e598a5e02792dc86374
출처 데이터셋
uspto-grants-1992_07
특허 번호
US05134147

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