2-Bromomethylnaphthalene → 3-Methoxy-4-(naphth-2-ylmethoxy)bromobenzene

HRID 654823Notes

Reaction equation

Br[CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.[Br:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[C:16]([O:21][CH3:22])[CH:15]=1>>[CH3:22][O:21][C:16]1[CH:15]=[C:14]([Br:13])[CH:19]=[CH:18][C:17]=1[O:20][CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1

Participants

Reactant 2

HCID 703202-Bromomethylnaphthalene

HCID 2622344-Bromo-2-methoxyphenol

Product 1

HCID 200806073-Methoxy-4-(naphth-2-ylmethoxy)bromobenzeneYield 62%

Procedure

Using the procedure described in Example 1, 2-bromomethylnaphthalene was reacted with 4-bromo-2-methoxyphenol to give 3-methoxy-4-(naphth-2-ylmethoxy)bromobenzene in 62% yield, m.p. 108° C.

Sources & evidence

ORD record: ord-1baa5dd3d37b4175bada2aecc2d67e09
Source dataset: uspto-grants-1992_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05134148

Reaction notes

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