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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655109Generated: October 31, 2026

Hydrochloric Acid → HCID 86638830, compound

https://huagongshe.com/reaction/655109

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 59185401HCID 59185401—
SolventEthyl AcetateHCID 8857—
ProductHCID 86638830HCID 86638830—

Reaction Steps

To a solution of (2S)-2-[(tert-butoxycarbonyl)-amino]-propyl pivaloate (1.0 eq.) in EtOAc (0.6 M) was added 4N HCl in dioxane (10 eq.). The reaction mixture was stirred for 2.5 h and then the solvent was evaporated in vacuo to give a solid that was washed with Et2O and dried.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071568B2
Source datasetuspto-grants-2011_12
ORD IDord-16a40a4ffab941b18951a14abaa35f13
Source noteuspto-grants-2011_12