Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655123Generated: October 30, 2026

Potassium Carbonate → HCID 86645699, compound

https://huagongshe.com/reaction/655123

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 86645700HCID 86645700—
SolventChloroform methanolHCID 21584188—
SolventWater methylene chlorideHCID 21908982—
ProductHCID 86645699HCID 86645699—

Reaction Steps

A solution of acetic acid (2R,3R,4S,5S)-4-acetoxy-5-(3-acetoxymethyl-isoxazol-5-yl)-2-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3-yl ester (Step CG1) in MeOH/chloroform (3:1 MeOH/chloroform) is treated with saturated potassium carbonate solution. After stirring at RT overnight, the reaction is diluted with DCM/water and the organic portion is separated. The organic portion is concentrated in vacuo to afford the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071565B2
Source datasetuspto-grants-2011_12
ORD IDord-56d77f30f125434db7ea422429a2245c
Source noteuspto-grants-2011_12