Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Hydroxy-4-nitrobenzaldehyde | HCID 69712 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Methoxy-4-nitrobenzaldehyde | HCID 11492043 | — |
Reaction Steps
A mixture of 3-hydroxy-4-nitrobenzaldehyde (51.3 g), iodomethane (38.3 ml) and K2CO3 (85 g) in DMF (250 ml) was stirred at 60° C. for 1 h. The reaction mixture was cooled to room temperature and poured into water (600 ml). The solids were collected by filtration and dried in vacuo (50° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08071587B2 |
|---|
| Source dataset | uspto-grants-2011_12 |
|---|
| ORD ID | ord-7d54f697937248188e281102ed4e2acc |
|---|
| Source note | uspto-grants-2011_12 |
|---|
