Potassium Carbonate → HCID 59320232, compound

Participants

Reaction Conditions

Reaction Steps

To a 5 ml microwave vial 1 ml of methanol was added followed by 15 mg of potassium carbonate, and 25 mg (0.067 mmol) of 6-(6-chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoline. The reaction mixture was heated for 3800 seconds at 130° C. in a microwave. The reaction mixture was then filtered and purified by preparatory HPLC to return the title compound (11.6 mg, 47%). Analytical data is presented in Table 2.

Provenance & Evidence