(4-Methoxyphenyl)boronic acid → HCID 59354830, compound

HRID 655384Notes

Reaction equation

HRID 655384 reaction equation
N1[CH:6]=[CH:5][C:4]([C:7]2[C:11]3([CH2:13][CH2:12]3)[O:10][C:9](=[O:14])[C:8]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][C:23]3[CH:32]=[CH:31][C:30]4[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=4)[N:24]=3)=[CH:17][CH:16]=2)=[CH:3][CH:2]=1.[CH3:33][O:34][C:35]1C=CC(B(O)O)=CC=1>>[CH3:33][O:34][C:35]1[CH:2]=[CH:3][C:4]([C:7]2[C:11]3([CH2:13][CH2:12]3)[O:10][C:9](=[O:14])[C:8]=2[C:15]2[CH:16]=[CH:17][C:18]([O:21][CH2:22][C:23]3[CH:32]=[CH:31][C:30]4[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=4)[N:24]=3)=[CH:19][CH:20]=2)=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 59354789HCID 59354789, compound

Product 1

HCID 59354830HCID 59354830, compoundYield 18%

Procedure

Following the procedure for the preparation of 7-(pyridin-4-yl)-6-(4-(quinolin-2-ylmethoxy)phenyl)-4-oxaspiro[2.4]hept-6-en-5-one (Example 26) using 4-methoxyphenylboronic acid provided the title compound.

Sources & evidence

ORD record
ord-972707b2c84946e89f3ab85c0f28c762
Source dataset
uspto-grants-2011_12
Patent number
US08071595B2

Reaction notes

Loading…