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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655398Generated: October 30, 2026

Thionyl Chloride → HCID 59354817, compound

https://huagongshe.com/reaction/655398

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant2-(4-(Quinolin-2-ylmethoxy)phenyl)acetic acidHCID 14500235—
ProductHCID 59354817HCID 5935481795%

Reaction Steps

A mixture of acid 2-(4-(quinolin-2-ylmethoxy)phenyl)acetic acid (2.0 g, 6.8 mmol) in SOCl2 (10 mL) was stirred at RT for 2 h under an inert atmosphere. The reaction was concentrated in vacuo to afford 2-(4-(quinolin-2-ylmethoxy)phenyl)acetyl chloride (2.0 g, 95%) as a light yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071595B2
Source datasetuspto-grants-2011_12
ORD IDord-fd417897652d4f0c990a4608ee0cbed9
Source noteuspto-grants-2011_12