Hydrochloric Acid → HCID 67080751, compound

Participants

Reaction Steps

In analogy to the procedure described in intermediate 5E, 4-[(S)-3-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-1-hydroxymethyl-propyl]-5-oxo-[1,4]diazepane-1-carboxylic acid benzyl ester and 0.1 eq. of 1 M aq. hydrochloric acid solution and Pd/C was hydrogenated to give the title compound in quantitative yield as a white gum. MS: 312.2 (MH+).

Provenance & Evidence