HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-chloro-3-isocyanato- → HCID 59149891, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-chloro-3-isocyanato- | HCID 17968 | — |
| Reactant | HCID 68536587 | HCID 68536587 | — |
| Product | HCID 59149891 | HCID 59149891 | 59% |
Reaction Steps
In analogy to the procedure described in example 58F, (S)-4-((S)-4-hydroxy-6-aza-spiro[2. 5]oct-6-yl)-2-((R)-3-methyl-7-oxo-[1,4]diazepan-1-yl)-butyric acid methyl ester dihydrochloride and 3-chlorophenyl isocyanate gave the title compound in 59% yield as off-white solid. MS: 506.2 (MH+, 1Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071586B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-26d49720d80b4763ad3bd809737fe12b |
| Source note | uspto-grants-2011_12 |