HRID655578

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID44541812

未命名化合物

2 次

反应SMILES：COC[C@H](CC=O)N1C[C@@H](C)N(C(=O)OC(C)(C)C)CCC1=O

HCID86638117

未命名化合物

PRODUCTS

产物

反应SMILES：COC[C@H](CCN1CCC2(CC2)[C@H](O)C1)N1C[C@@H](C)N(C(=O)OC(C)(C)C)CCC1=O

HCID67080743

未命名化合物

收率 94%

PROCEDURE

实验过程

In analogy to the procedure described for example 58D, (R)-4-((S)-1-methoxymethyl-3-oxo-propyl)-2-methyl-5-oxo-[1,4]diazepane-1-carboxylic acid tert-butyl ester and (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride (intermediate 2) gave the title compound in 94% yield as yellow viscous oil. MS: 440.4 (MH+).