反应详情

Then, 3.7 ml of concentrated hydrochloric acid was added to a methanol solution of 9.5 g of 1-benzo[b]thiophen-4-yl-piperazine, and the solvent was evaporated under reduced pressure. Ethyl acetate was added to the obtained residue and precipitated crystals were obtained by filtration. Recrystallization was performed from methanol to obtain 1-benzo[b]thiophen-4-yl-piperazine hydrochloride as colorless needle-like crystals.

1. customthe solvent was evaporated under reduced pressure
2. additionEthyl acetate was added to the obtained residue
3. customprecipitated crystals
4. customwere obtained by filtration
5. customRecrystallization