反应详情

温度

100 °C

The mixture of 5 g of 2-nitro-5-chlorobenzoic acid and 15 mL of 60% aqueous dimethylamine solution is stirred at 100° C. for 6 hours. The reaction mixture is evaporated, the residue dissolved in 15 mL of water. The pH of the mixture is adjusted to 6 with acetic acid. The precipitated yellow crystalline material is filtered off, washed with water and dried, to obtain 3.4 g of the title compound. Mp.: 189° C.

1. customThe reaction mixture is evaporated
2. dissolutionthe residue dissolved in 15 mL of water
3. filtrationThe precipitated yellow crystalline material is filtered off
4. washwashed with water
5. customdried