反应详情

2-[4-(2-Fluorophenoxy)phenyl]propionic acid (2.32 g.) in ethanol (16 ml.) containing concentrated sulfuric acid (0.5 ml.) were refluxed for 5 hours and the alcohol removed. After dilution with water the product was isolated in ether and distilled to give ethyl 2-[4-(2-fluorophenoxy)phenyl]propionate, b.p. 176°-177° C./2.5 mm.

1. temperaturewere refluxed for 5 hours
2. customthe alcohol removed
3. customAfter dilution with water the product was isolated in ether
4. distillationdistilled