HCID 69231152, compound → HCID 69230028, compound

HRID 656301Notes

Reaction equation

HRID 656301 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]([C:12]#[N:13])[N:9]([CH3:11])[CH:10]=1)(=[O:4])=[O:3].[H][H]>[Pd].CO>[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]([CH2:12][NH2:13])[N:9]([CH3:11])[CH:10]=1)(=[O:3])=[O:4]

Participants

5

Reactant 2

HCID 69231152HCID 69231152, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 69230028HCID 69230028, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Compound 22-7 (150 mg) and 10% palladium/carbon (catalytic amount), together with methanol (10 ml), were poured into reactor and the reactor was filled with hydrogen gas, followed by stirring at room temperature for 24 hours. After the completion of the reaction, the resulting mixture was filtered through celite and concentrated under reduced pressure. The following procedure was carried out using the obtained residue which was not purified.

Workup

  1. customAfter the completion of the reaction
  2. filtrationthe resulting mixture was filtered through celite and
  3. concentrationconcentrated under reduced pressure
  4. customwas not purified

Sources & evidence

ORD record
ord-c148d03891eb44a0a1ae87efaeb68fde
Source dataset
uspto-grants-2011_12
Patent number
US08071650B2

Reaction notes

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