HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10225335, compound → HCID 178440922, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10225335 | HCID 10225335 | — |
| Reactant | CH2N2Pb | HCID 22262466 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178440922 | HCID 178440922 | 78.1% |
Reaction Steps
1-(4-t-butylbenzyl)-3-(2,6-difluoro-3-methanesulfonylaminobenzyl)thiourea (44 mg) and lead cyanamide (30 mg) were added to ethyl acetate (10 ml) and the mixture was refluxed for 18 hours. The resulting mixture was purified by column-chromatogrphy (hexane/ethyl acetate=1/1) to yield the compound 31-7 (35 mg, 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071650B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-c21b4c9ba8074ea691c90ca35df574fe |
| Source note | uspto-grants-2011_12 |