N-Hydroxyphthalimide → HCID 57999105, compound

HRID 656563Notes

Reaction equation

HRID 656563 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][OH:6].O[N:8]1[C:12](=[O:13])[C:11]2=[CH:14][CH:15]=[CH:16][CH:17]=[C:10]2[C:9]1=[O:18]>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][O:6][N:8]1[C:12](=[O:13])[C:11]2[C:10](=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:9]1=[O:18]

Participants

3

Reactant 2

HCID 10665N-HydroxyphthalimideHCID 741163-Methoxy-1-propanol

Product 1

HCID 57999105HCID 57999105, compoundYield 94.9%

Procedure

2-(3-Methoxypropoxy)isoindoline-1,3-dione (2C) was prepared from 3-methoxypropan-1-ol and N-hydroxyphthalimide by a procedure analogous to Example 2A, Step 1 (3.71 g, 94.9% yield). ESI-MS: m/z 236.3 (M+H)+.

Sources & evidence

ORD record
ord-36c780301b4b47f8ad88ec724f422b19
Source dataset
uspto-grants-2011_12
Patent number
US08071766B2

Reaction notes

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