HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Methoxyethoxy)-1H-isoindole-1,3(2H)-dione → tert-butyl N-(2-(aminooxy)ethyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Methoxyethoxy)-1H-isoindole-1,3(2H)-dione | HCID 12919115 | — |
| Reactant | tert-Butyl (2-((1,3-dioxoisoindolin-2-yl)oxy)ethyl)carbamate | HCID 18929164 | — |
| Product | tert-butyl N-(2-(aminooxy)ethyl)carbamate | HCID 15610443 | 58% |
Reaction Steps
2E was deprotected as previously described in 2A, Step 2 to give tert-butyl 2-(aminooxy)ethylcarbamate (2F, 1.26 g, 58% yield). 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 1.45 (s, 9H) 3.37 (q, J=5.31 Hz, 2H) 3.62-3.85 (m, 2H) 4.90 (br. s., 1H) 5.47 (br. s., 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071766B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-2b1e0ddd95614fd19e7ba49713a87d9d |
| Source note | uspto-grants-2011_12 |