反应详情

A suspension of 2,3,8,9-tetrahydro-5-phenyl-9-(phenylmethylene)-5H,6H-thiazolo[3,2-a]thiopyrano[4,3-d]pyrimidine (3.0 g, 0.0079 mole) in 25 ml of MeOH is treated with 0.92 g (0.0079 mole) of maleic acid. The solution is evaporated in vacuo to give an oil which gradually solidifies. The yield is 3.7 g, m.p. 142°-144°. Crystallization from 15 ml of MeCN gives 3.0 g (77%) of cream colored product, m.p. 143°-145°.

1. customThe solution is evaporated in vacuo
2. customto give an oil which
3. customCrystallization from 15 ml of MeCN
4. customgives 3.0 g (77%) of cream colored product, m.p. 143°-145°