HuagongsheHuagongshe Chemistry Print Report · For research reference only
Maleic Acid → HCID 131711357, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Maleic Acid | HCID 444266 | — |
| Reactant | 2,3,8,9-Tetrahydro-5-phenyl-9-(phenylmethylene)-5H,6H-thiazolo[3,2-a]thiopyrano[4,3-d]pyrimidine | HCID 21786672 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 131711357 | HCID 131711357 | — |
Reaction Steps
A suspension of 2,3,8,9-tetrahydro-5-phenyl-9-(phenylmethylene)-5H,6H-thiazolo[3,2-a]thiopyrano[4,3-d]pyrimidine (3.0 g, 0.0079 mole) in 25 ml of MeOH is treated with 0.92 g (0.0079 mole) of maleic acid. The solution is evaporated in vacuo to give an oil which gradually solidifies. The yield is 3.7 g, m.p. 142°-144°. Crystallization from 15 ml of MeCN gives 3.0 g (77%) of cream colored product, m.p. 143°-145°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04128647 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-521b210dea4649c4b26775bb00b2e438 |
| Source note | uspto-grants-1978_12 |