反应详情

Ethyl 2-hydroxy-4-methyl-2-(trifluoromethyl)pentenoate is used as starting material. 27.1 g (120 mmole) ethyl 2-hydroxy-4-methyl-2-(trifluoromethyl)pentenoate is emulsified in 60 mL water, the pH is adjusted to 8.0 with sodium hydroxide solution, the solution is stirred at room temperature. 6 g of the enzyme (Novozyme 388) is added at room temperature. The mixture is stirred for 10 hours under GC control.

1. addition6 g of the enzyme (Novozyme 388) is added at room temperature
2. stirringThe mixture is stirred for 10 hours under GC control