Sulfuric Acid → HCID 86050515, compound

HRID 656718Notes

Reaction equation

HRID 656718 reaction equation
S(=O)(=O)(O)O.[CH:6]([OH:15])([C:11]([F:14])([F:13])[F:12])[C:7]([F:10])([F:9])[F:8].C[O:17][CH:18](O)[C:19]([F:22])([F:21])[F:20]>>[C:19]([CH:18]([O:15][CH:6]([C:11]([F:14])([F:13])[F:12])[C:7]([F:10])([F:9])[F:8])[OH:17])([F:22])([F:21])[F:20]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 98922,2,2-Trifluoro-1-methoxyethanolHCID 135291,1,1,3,3,3-Hexafluoro-2-propanol

Product 1

HCID 86050515HCID 86050515, compound

Conditions

Temperature
0 °C

Procedure

This reaction was carried out in essentially the same manner as described in Example 1 using charges of sulfuric acid (175 g), (CF3)2CHOH (70.6 g, 0.42 mole, Synquest Labs) and trifluoroacetaldehyde methyl hemiacetal (Alfa Aesar, 50 g, 90% purity, 0.346 mole). In this case the receiver was cooled in an ice water bath to about 0° C. to avoid solidification of the alcohol. The receiver had gained 8.6 g in weight and this solution was used without purification in the next step.

Workup

  1. customthis solution was used without purification in the next step

Sources & evidence

ORD record
ord-cd1913e3086d4c10a73cc1e2b0e2702c
Source dataset
uspto-grants-2011_12
Patent number
US08071816B2

Reaction notes

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