m-Chloroperbenzoic acid → {3-[4-(2,2-Dimethyl-propionylamino)-2-(2-methyl-propane-2-sulfinylmethyl)-phenoxy]-4-hydroxy-phenyl}-acetic acid

HRID 656792Notes

Reaction equation

HRID 656792 reaction equation
[C:1]([S:5][CH2:6][C:7]1[CH:24]=[C:23]([NH:25][C:26](=[O:31])[C:27]([CH3:30])([CH3:29])[CH3:28])[CH:22]=[CH:21][C:8]=1[O:9][C:10]1[CH:11]=[C:12]([CH2:17][C:18]([OH:20])=[O:19])[CH:13]=[CH:14][C:15]=1[OH:16])([CH3:4])([CH3:3])[CH3:2].ClC1C=CC=C(C(OO)=[O:40])C=1>>[CH3:28][C:27]([CH3:30])([CH3:29])[C:26]([NH:25][C:23]1[CH:22]=[CH:21][C:8]([O:9][C:10]2[CH:11]=[C:12]([CH2:17][C:18]([OH:20])=[O:19])[CH:13]=[CH:14][C:15]=2[OH:16])=[C:7]([CH2:6][S:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[O:40])[CH:24]=1)=[O:31]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 44600128{3-[2-tert-Butylsulfanylmethyl-4-(2,2-dimethyl-propionylamino)-phenoxy]-4-hydroxy-phenyl}-acetic acid

Product 1

HCID 44600129{3-[4-(2,2-Dimethyl-propionylamino)-2-(2-methyl-propane-2-sulfinylmethyl)-phenoxy]-4-hydroxy-phenyl}-acetic acid

Procedure

Prepared according to the procedure described in Example 2 using {3-[2-tert-butylsulfanylmethyl-4-(2,2-dimethyl-propionylamino)-phenoxy]-4-hydroxy-phenyl}-acetic acid and 3-chloroperbenzoic acid (1 equivalent).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ab2f7fff83d44b3dbd692bb0cd0063bb
Source dataset
uspto-grants-2011_12
Patent number
US08071807B2

Reaction notes

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