反应详情

温度

110 °C

7-(Methyloxy)quinoline (8.76 g; 55.09 mmol) and allyl iodide (19.72 ml; 110.18 mmol) were refluxed in toluene (120 ml) at 95° C. for 1 h, more allyl iodide (9.86 ml; 55.09 mmol) was added and the temperature of the reaction increased to 110° C. After a further 1 h the temperature of the reaction was increased to 120° C. and reaction continued for a further 0.5 h. The solvent was removed under vacuum and the resulting brown solid was washed with toluene and diethyl ether. The resultant solid were left to dry in a vacuum oven overnight to give the desired product (14.81 g; 82%)

1. temperatureAfter a further 1 h the temperature of the reaction was increased to 120° C.
2. customreaction
3. customThe solvent was removed under vacuum
4. washthe resulting brown solid was washed with toluene and diethyl ether
5. waitThe resultant solid were left
6. customto dry in a vacuum oven overnight