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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 656995Generated: October 28, 2026

Trifluoroacetic acid → HCID 68995872, compound

https://huagongshe.com/reaction/656995

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 69186360HCID 69186360—
SolventDichloromethaneHCID 6344—
ProductHCID 68995872HCID 6899587285.3%

Reaction Steps

A solution of 1,1-dimethylethyl {1-[2-(6,7-difluoro-2-oxo-1(2H)-quinoxalinyl)ethyl]-4-piperidinyl}(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-ylmethyl)carbamate (0.17 g, 0.305 mmol) in DCM (0.65 ml) was treated with trifluoroacetic acid (0.43 ml, 5.78 mmol) stirred at rt for 1 h and evaporated. The residue was triturated with ether and dried at 50° C. under vacuum to give the title compound (0.149 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071592B2
Source datasetuspto-grants-2011_12
ORD IDord-1fc27438639642d2b3963d3904604cc5
Source noteuspto-grants-2011_12