HCID 68809572, compound → 7-Methoxy-1,2-dihydroquinolin-2-one

HRID 657001Notes

Reaction equation

HRID 657001 reaction equation
C(O/[CH:4]=[CH:5]/[C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=1)=[O:7])C>OS(O)(=O)=O>[CH3:16][O:15][C:11]1[CH:10]=[C:9]2[C:14]([CH:4]=[CH:5][C:6](=[O:7])[NH:8]2)=[CH:13][CH:12]=1

Participants

3

Reactant 1

HCID 68809572HCID 68809572, compound

Product 1

HCID 299427567-Methoxy-1,2-dihydroquinolin-2-oneYield 60.6%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

(2E)-3-(Ethyloxy)-N-[3-(methyloxy)phenyl]-2-propenamide (25 g; 0.113 mol) was dissolved in conc. H2SO4 and stirred for 1 h. The reaction mixture was poured onto ice and filtered. The crude product was washed with water and dried to yield the title compound (12 g; 60%) as a tan solid.

Workup

  1. additionThe reaction mixture was poured onto ice
  2. filtrationfiltered
  3. washThe crude product was washed with water
  4. customdried

Sources & evidence

ORD record
ord-fe817eb91bf8491cbb6cd5145a3fa0a4
Source dataset
uspto-grants-2011_12
Patent number
US08071592B2

Reaction notes

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