HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23003649, compound → HCID 23003688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23003649 | HCID 23003649 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 23003688 | HCID 23003688 | 100% |
Reaction Steps
A solution of 1,1-dimethylethyl {[4-hydroxy-1-(phenylmethyl)-3-piperidinyl]methyl}carbamate (3.7 g, 11.56 mmol) in methanol (70 ml) was stirred under hydrogen at room temperature with 20% palladium hydroxide/carbon (moist, 0.7 g) overnight. After filtration through kieselguhr, the methanol was evaporated to afford the desired product (2.65 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071592B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-01d2e1246f69465389903d35c1b29a0d |
| Source note | uspto-grants-2011_12 |