Sodium Chloride → HCID 68954890, compound

HRID 657451Notes

Reaction equation

HRID 657451 reaction equation
[CH3:1][C:2]([CH3:14])([C:10]([CH3:13])=[CH:11][CH3:12])[CH2:3][CH2:4]/[CH:5]=[CH:6]/[C:7]([OH:9])=O.ClC(OCC)=O.C(N(CC)CC)C.[CH:28]1([NH2:31])[CH2:30][CH2:29]1.[Cl-].[Na+]>>[CH:28]1([NH:31][C:7](=[O:9])/[CH:6]=[CH:5]/[CH2:4][CH2:3][C:2]([CH3:1])([CH3:14])[C:10]([CH3:13])=[CH:11][CH3:12])[CH2:30][CH2:29]1

Participants

6

Reactant 5

HCID 5234Sodium ChlorideHCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 69828CyclopropylamineHCID 86594596HCID 86594596, compound

Product 1

HCID 68954890HCID 68954890, compoundYield 40%

Procedure

4-(2,2,3-Trimethyl-3-penten-1-yl)-2E-butenoic acid 1 eq, ethyl chloroformate 1.5 eq, triethylamine 1.5 eq, cyclopropylamine 1.5 eq, quench with 10% sodium chloride solution, yield=40%.

Sources & evidence

ORD record
ord-68ee32b1c60e4c32b4cfeb9d8f059d7e
Source dataset
uspto-grants-2011_12
Patent number
US08075937B2

Reaction notes

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