Bromomethylcyclopropane → HCID 59442685, compound

HRID 657500Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([C:8]2([OH:22])[CH2:13][CH2:12][C:11]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)([C:14]#[N:15])[CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1.Br[CH2:24][CH:25]1[CH2:27][CH2:26]1>>[Br:1][C:2]1[CH:3]=[C:4]([C:8]2([O:22][CH2:24][CH:25]3[CH2:27][CH2:26]3)[CH2:9][CH2:10][C:11]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)([C:14]#[N:15])[CH2:12][CH2:13]2)[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 81503Bromomethylcyclopropane

HCID 59442696HCID 59442696, compound

Product 1

HCID 59442685HCID 59442685, compound

Procedure

The title compound was prepared from 4-(3-bromophenyl)-4-hydroxy-1-phenylcyclohexanecarbonitrile and bromomethylcyclopropane according to the process described in Example 41.

Sources & evidence

ORD record: ord-32641a85d9bb430fa21951f59c7411c7
Source dataset: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08076324B2

Reaction notes

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