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HRID65751

反应详情

EQUATION

反应方程式

HRID 65751 的结构方程式

REACTANTS

反应物

2
结构：CC(C)N=C=O
HCID61277

Propane, 2-isocyanato-

C4H7NO

结构：CN(C)Cc1ccc(CSCCN)o1
HCID162203

5-((2-Aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine

C10H18N2OS

PRODUCTS

生成物

1
结构：CC(C)NC(=O)NCCSCc1ccc(CN(C)C)o1
HCID23452144

未命名化合物

收率 93.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (2.14 g) and isopropylisocyanate (0.89 g) were dissolved in acetonitrile and allowed to stand overnight. Solvents were removed and the residue recrystallised from methanol:ether to give N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea as crystals m.p. 65°-67° (2.8 g).

WORKUP

后处理

  1. customSolvents were removed
  2. customthe residue recrystallised from methanol