Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide dimethyl acetal → N-[1-Dimethylaminomethylidene]-3-methylsulfanylbenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | 3-Methylsulfanylbenzamide | HCID 44581297 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-[1-Dimethylaminomethylidene]-3-methylsulfanylbenzamide | HCID 59442543 | — |
반응 단계
8.5 g of 3-methylsulfanylbenzamide and 18 ml of dimethylformamide dimethyl acetal were heated at 120° C. while the formed methanol was eliminated by distillation. After heating for 3 h, the volatiles were removed in vacuo. The crude product was purified by flash chromatography (300 g silica gel; DCM/MOH, gradient from 100:0 to 95:5). 8 g of the title compound were obtained as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08076324B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-af8e0a68413e4818b933fa093ce5b3de |
| 출처 메모 | uspto-grants-2011_12 |