HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 68531538, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 18467790 | HCID 18467790 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68531538 | HCID 68531538 | — |
Reaction Steps
7 g (41.3 mmoles) of 5,6-dihydrocyclobuta[4,5]benzo[1,2-b]furan-6-carbonitrile are dissolved in 490 mL of ethanol. 70 mL of 28% NH4OH solution and 1 g of Raney nickel are added. Hydrogenation is carried out under a pressure of 5 bar, at 25° C., for 3 days. Filtration over Celite and evaporation of the filtrate to dryness are carried out. The expected product is obtained in the form of a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076325B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-c142936ea096490596a351b5afc1ba5b |
| Source note | uspto-grants-2011_12 |