HRID657558

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22262358

3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-triene-7-methanamine

C12H17NO2

HCID68533314

未命名化合物

结构：COc1cc2c(cc1OC)CCN(C(=O)CCN(C)CC1Cc3cc(OC)c(OC)cc31)CC2.Cl

HCID68972400

未命名化合物

PRODUCTS

生成物

结构：COc1cc2c(cc1OC)CCN(C(=O)CCN(C)CCC1Cc3cc(OC)c(OC)cc3C1)CC2.Cl

HCID68971773

未命名化合物

PROCEDURE

实验过程

Obtained in the same manner as the product of Example 1, but with replacement of the [(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]methylamine in Step 4 by [2-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)ethyl]methylamine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f1116da1ba774c22903601e50a686593
来源数据集: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08076325B2
来源说明: uspto-grants-2011_12

反应 SMILES

[ClH:1].COC1C=C2C(=CC=1OC)C([CH2:14][N:15]([CH3:35])[CH2:16][CH2:17][C:18]([N:20]1[CH2:26][CH2:25][C:24]3[CH:27]=[C:28]([O:33][CH3:34])[C:29]([O:31][CH3:32])=[CH:30][C:23]=3[CH2:22][CH2:21]1)=[O:19])C2.COC1C=C2C(=CC=1OC)C(CNC)C2.[CH3:51][O:52][C:53]1[CH:54]=[C:55]2[C:59](=[CH:60][C:61]=1[O:62][CH3:63])[CH2:58][CH:57]([CH2:64]CNC)[CH2:56]2>>[ClH:1].[CH3:63][O:62][C:61]1[CH:60]=[C:59]2[C:55](=[CH:54][C:53]=1[O:52][CH3:51])[CH2:56][CH:57]([CH2:64][CH2:14][N:15]([CH3:35])[CH2:16][CH2:17][C:18]([N:20]1[CH2:26][CH2:25][C:24]3[CH:27]=[C:28]([O:33][CH3:34])[C:29]([O:31][CH3:32])=[CH:30][C:23]=3[CH2:22][CH2:21]1)=[O:19])[CH2:58]2