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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 657558Generated: November 2, 2026

1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine → N-[2-(5,6-Dimethoxy-2,3-dihydro-1H-inden-2-yl)ethyl]-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxopropan-1-amine hydrochloride

https://huagongshe.com/reaction/657558

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamineHCID 22262358—
Reactant[2-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)ethyl]methylamineHCID 68533314—
ReactantN-[(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxopropan-1amine hydrochlorideHCID 68972400—
ProductN-[2-(5,6-Dimethoxy-2,3-dihydro-1H-inden-2-yl)ethyl]-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxopropan-1-amine hydrochlorideHCID 68971773—

Reaction Steps

Obtained in the same manner as the product of Example 1, but with replacement of the [(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]methylamine in Step 4 by [2-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)ethyl]methylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076325B2
Source datasetuspto-grants-2011_12
ORD IDord-f1116da1ba774c22903601e50a686593
Source noteuspto-grants-2011_12