HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 3-(7,8-Dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-[(5-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]-3-oxopropan-1-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | N-[(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxopropan-1amine hydrochloride | HCID 68972400 | — |
| Product | 3-(7,8-Dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-[(5-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]-3-oxopropan-1-amine hydrochloride | HCID 68976133 | — |
Reaction Steps
Obtained in the same manner as the product of Example 1, but with replacement of the [(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]methylamine in Step 4 by the product of Preparation 9 and of the THF by dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076325B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-0fc3aad22f7647feba17c7861cec7257 |
| Source note | uspto-grants-2011_12 |