HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 68975097, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one | HCID 1482373 | — |
| Reactant | 8-methoxy-2,3-dihydro-1H-3-benzazepin-2-one | HCID 4220093 | — |
| Reactant | 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane, (S)- | HCID 11506616 | — |
| Reactant | N-[(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxopropan-1amine hydrochloride | HCID 68972400 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68975097 | HCID 68975097 | — |
Reaction Steps
Obtained in the same manner as the product of Example 1, but with replacement, in Step 1, of the 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one by 8-methoxy-1,3-dihydro-2H-3-benzazepin-2-one and, in Step 4, of the racemic (3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]methylamine by {[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}amine and of the THF by dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076325B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-1cd759714e554dd2b99c3db9c72976b2 |
| Source note | uspto-grants-2011_12 |