HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 66764225, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | [5-(Methylsulfanyl)thiophen-2-yl]boronic acid | HCID 2794627 | — |
| Reactant | HCID 57528563 | HCID 57528563 | — |
| Product | HCID 66764225 | HCID 66764225 | — |
Reaction Steps
This compound is obtained according to the method described in stage 1.6 of Example 1, using 5-(6-chloropyridazin-3-yl)-1-azabicyclo[3.2.1]octane, prepared according to stage 1.5 of Example 1, and 5-methylsulfanyl-2-thienylboronic acid. The hydrochloride thereof is prepared by treatment of the base with a solution of hydrochloric acid in propan-2-ol, and the crystals obtained are collected by filtration and dried under vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076340B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-f8cd46309ec0442f95f5ea7d5fe1068b |
| Source note | uspto-grants-2011_12 |