HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 11979212, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 23150304 | HCID 23150304 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 11979212 | HCID 11979212 | 33% |
Reaction Steps
Following the procedure described in example 36, but starting from 1-{3-[4′-(3-chloropropoxy)biphenyl-4-yloxy]propyl}piperidine (250 mg), pyrrolidine (138 mg) and potassium carbonate (360 mg) in N,N-dimethylformamide (2 mL) affords 90 mg of 1-(3-{[4′-(3-piperidinopropoxy)biphenyl-4-yl]oxy}propyl)pyrrolidine as white crystals melting at 105-108° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076329B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-aace567a9e59414f945e990b908cffe0 |
| Source note | uspto-grants-2011_12 |