HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glutaric Acid → HCID 178484388, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glutaric Acid | HCID 743 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178484382 | HCID 178484382 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178484388 | HCID 178484388 | 86.9% |
Reaction Steps
10.0 g of metformin, 2.40 g of sodium hydroxide and 3.98 g of glutaric acid were stirred in 150 ml of ethyl alcohol at a temperature of 70° C., and then methylene chloride was added thereto. The produced inorganic salt was filtered and ethyl acetate was added to the filtered solution. The produced crystal was filtered and dried in hot air, thus obtaining 6.79 g (yield: 57.7%) of metformin glutarate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076377B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-ecf0fa3b2337412185e3c44166b38cbb |
| Source note | uspto-grants-2011_12 |