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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658122Generated: October 30, 2026

Glutaric Acid → HCID 178484388, compound

https://huagongshe.com/reaction/658122

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlutaric AcidHCID 743—
ReactantDichloromethaneHCID 6344—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178484382HCID 178484382—
SolventEthanolHCID 702—
ProductHCID 178484388HCID 17848438886.9%

Reaction Steps

10.0 g of metformin, 2.40 g of sodium hydroxide and 3.98 g of glutaric acid were stirred in 150 ml of ethyl alcohol at a temperature of 70° C., and then methylene chloride was added thereto. The produced inorganic salt was filtered and ethyl acetate was added to the filtered solution. The produced crystal was filtered and dried in hot air, thus obtaining 6.79 g (yield: 57.7%) of metformin glutarate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076377B2
Source datasetuspto-grants-2011_12
ORD IDord-ecf0fa3b2337412185e3c44166b38cbb
Source noteuspto-grants-2011_12