HuagongsheHuagongshe Chemistry Print Report · For research reference only
Adipic Acid → HCID 178484387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Adipic Acid | HCID 196 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 178484382 | HCID 178484382 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178484387 | HCID 178484387 | 146.2% |
Reaction Steps
10.00 g of the metformin free-base and 4.411 g of adipic acid were stirred in 150 ml of methyl alcohol at 40° C., and then ethyl acetate was added thereto. The produced crystal was filtered and dried in hot air, thus obtaining 12.06 g (yield: 98.9%) of metformin adipate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076377B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-77f55f0e945b4a69a64eac2d9498f297 |
| Source note | uspto-grants-2011_12 |