(2-Chloro-3-nitrophenyl)methanol → 2-Chloro-3-nitrobenzaldehyde

HRID 658170Notes

Reaction equation

HRID 658170 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:11][OH:12]>C(Cl)(Cl)Cl.[O-2].[Mn+4].[O-2]>[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:11]=[O:12]

Participants

4

Reactant 1

HCID 15132843(2-Chloro-3-nitrophenyl)methanol

Product 1

HCID 126677132-Chloro-3-nitrobenzaldehyde

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6212ChloroformSolvent

Procedure

9.2 g (49.05 mmol) of (2-chloro-3-nitrophenyl)methanol and 13.2 g (151.8 mmol) of activated manganese(IV) oxide in 50 ml of chloroform are heated under reflux for 20 h. The mixture is filtered through kieselguhr, concentrated and dried under high vacuum. The resulting title compound is directly reacted further.

Workup

  1. temperatureunder reflux for 20 h
  2. filtrationThe mixture is filtered through kieselguhr
  3. concentrationconcentrated
  4. customdried under high vacuum
  5. customThe resulting title compound is directly reacted further

Sources & evidence

ORD record
ord-396e3c02c73c40b7b6210436ec567935
Source dataset
uspto-grants-2011_12
Patent number
US08076355B2

Reaction notes

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