HRID658314

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID88262

[1,1'-Biphenyl]-4-ol, 4'-(1,1-dimethylethyl)-

C16H18O

结构：COC(=O)CCNC(=O)c1ccc(C(CO)CCCC(F)(F)F)cc1

HCID67485530

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1ccc(-c2ccc(OCC(CCCC(F)(F)F)c3ccc(C(=O)NCCC(=O)O)cc3)cc2)cc1

HCID24765239

未命名化合物

PROCEDURE

实验过程

The title compound is prepared by essentially following the procedures as described in Example 8, using 4′-tert-butyl-biphenyl-4-ol and 3-[4-(5,5,5-trifluoro-1-hydroxymethyl-pentyl)-benzoylamino]-propionic acid methyl ester as starting materials. MS (ES): 554.2 [M+H]−.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-094c995c604b4de08db0a9cd4f7eeed4
来源数据集: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08076374B2

反应 SMILES

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].C[O:19][C:20](=[O:42])[CH2:21][CH2:22][NH:23][C:24](=[O:41])[C:25]1[CH:30]=[CH:29][C:28]([CH:31]([CH2:39]O)[CH2:32][CH2:33][CH2:34][C:35]([F:38])([F:37])[F:36])=[CH:27][CH:26]=1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:12]=[CH:13][C:14]([O:17][CH2:39][CH:31]([C:28]3[CH:29]=[CH:30][C:25]([C:24]([NH:23][CH2:22][CH2:21][C:20]([OH:42])=[O:19])=[O:41])=[CH:26][CH:27]=3)[CH2:32][CH2:33][CH2:34][C:35]([F:36])([F:38])[F:37])=[CH:15][CH:16]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]