HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-hydroxypyridine → HCID 24765339, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-hydroxypyridine | HCID 819821 | — |
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | HCID 67485977 | HCID 67485977 | — |
| Product | HCID 24765339 | HCID 24765339 | — |
Reaction Steps
The title compound is prepared by essentially following the procedures as described in Example 21, using 3-[4-(1-hydroxymethyl-butyl)-benzoylamino]-propionic acid methyl ester and 6-chloro-pyridin-3-ol as starting materials in Step A, followed by 4-trifluoromethyl phenyl boronic acid in Step B. MS (ES): 499.2 [M+H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076374B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-3f3cf62c62eb4d299013cbf0e7917d8a |
| Source note | uspto-grants-2011_12 |