反应详情

温度

90 °C

[4-(5-Ethoxy-4H-[1,2,4]triazol-3-yl)-pyridin-3-yl]-(2-fluoro-4-iodo-phenyl)-amine (80 mg) was added conc. HCl (4 mL). The reaction mixture was stirred at 90° C. for 4 hr, cooled and filtered, the solid was washed with water and methanol. Yield: white solid 30 mg. LC-MS (Method A) [5.23 min; 398(M+1)]

1. temperaturecooled
2. filtrationfiltered
3. washthe solid was washed with water and methanol
4. customLC-MS (Method A) [5.23 min; 398(M+1)]