2-Methyl-6-nitrobenzoxazole → 2-Methyl-1,3-benzoxazol-6-amine

HRID 658445Notes

Reaction equation

HRID 658445 reaction equation
[CH3:1][C:2]1[O:3][C:4]2[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.S1(=O)(=O)C=CC=C1>>[CH3:1][C:2]1[O:3][C:4]2[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

3

Reactant 2

HCID 797662-Methyl-6-nitrobenzoxazoleHCID 117926Thiophene, 1,1-dioxide

Product 1

HCID 5905392-Methyl-1,3-benzoxazol-6-amine

Procedure

This compound was prepared from 2-methyl-6-nitrobenzoxazole (2.0 g, 13.5 mmol) in the same manner described for 5-aminobenxo[b[thiophene 1,1-dioxide, affording 1.57 (94%) of the title compound as a brown solid. MS LC-MS (M+H)+=149.1, RT=0.77 min.

Sources & evidence

ORD record
ord-acc7a31ccb0249e498547c6fc92de01a
Source dataset
uspto-grants-2011_12
Patent number
US08076488B2

Reaction notes

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