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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658483Generated: October 26, 2026

2-amino-N-methylacetamide hydrochloride → HCID 58385419, compound

https://huagongshe.com/reaction/658483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-amino-N-methylacetamide hydrochlorideHCID 13842202—
Reactant4-(4-Aminophenoxy)pyridine-2-carboxylic acid methylcarbamoylmethylamideHCID 68429577—
ProductHCID 58385419HCID 58385419—

Reaction Steps

The title compound was prepared in the same manner described for 4-(4-aminophenoxy)pyridine-2-carboxylic acid methylcarbamoylmethylamide, substituting 2-amino-N,N′-dimethylacetamide hydrochloride for 2-amino-N-methylacetamide hydrochloride. 1H-NMR (DMSO-d6) δ 8.75 (t, J=4.8 Hz, 1H), 8.49 (d, J=5.4 Hz, 1H), 7.33 (d, J=2.7 Hz, 1H), 7.32 (d, J=2.7 Hz, 1H), 6.86 (d, J=8.7 Hz, 2H), 6.63 (d, J=9.0 Hz, 2H), 5.18 (s, 2H), 4.11 (d, J=5.4 Hz, 2H), 2.96 (s, 3H), 2.85 (s, 3H); MS LC-MS [M+H]+=315.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076488B2
Source datasetuspto-grants-2011_12
ORD IDord-b67ebb49ea4f45389e0d4a8751588112
Source noteuspto-grants-2011_12